学术报告：
a small ‘ship’ sails far: nuclear receptor shp
in liver metabolic homeostasis
王黎
美国尤他大学医学院（the university of utah school of medicine）副教授
地点：1#309
时间：5月17日（周五）上午9：00
报告提要：nuclear receptors are ligand-activated transcriptional regulators controlling key aspects of hepatic physiology and pathophysiology. nuclear receptors are involved in regulating lipid and bile acid homeostasis, drug metabolism, liver regeneration, fibrosis, and liver tumor formation. therefore nuclear receptors appear to be attractive therapeutic targets for a broad range of liver diseases including cholestatic and fatty liver disease, drug hepatotoxicity, viral hepatitis, liver fibrosis, and cancer. this talk is focused on the function of a unique orphan nuclear receptor, namely, small heterodimer partner, in metabolic liver diseases, regulation of microrna function and circadian clocks.
